YAP regulates cell mechanics by controlling focal adhesion assembly
Nature Communications, Published online: 15 May 2017; doi:10.1038/ncomms15321
The transcriptional co-activator YAP is known to operate downstream of mechanical signals arising from the cell niche. Here the authors demonstrate that YAP controls cell mechanics, force development and adhesion strength by promoting the transcription of genes related to focal adhesions.
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